Hematologic disease
| Hematologic disease | |
|---|---|
| Specialty | Hematology  | 
Hematologic diseases are disorders which primarily affect the blood and blood-forming organs. Hematologic diseases include rare genetic disorders, anemia, HIV, sickle cell disease and complications from chemotherapy or transfusions.
Myeloid
- Hemoglobinopathies (congenital abnormality of the hemoglobin molecule or of the rate of hemoglobin synthesis)
 - Anemias (lack of red blood cells or hemoglobin)
- Iron-deficiency anemia
 - Megaloblastic anemia
- Vitamin B12 deficiency
 - Folate deficiency
 
 - Hemolytic anemias (destruction of red blood cells)
- Genetic disorders of RBC membrane
 - Genetic disorders of RBC metabolism
 - Immune mediated hemolytic anemia (direct Coombs test is positive)
- Autoimmune hemolytic anemia
- Warm antibody autoimmune hemolytic anemia
- Idiopathic
 - Systemic lupus erythematosus (SLE)
 - Evans syndrome (antiplatelet antibodies and hemolytic antibodies)
 
 - Cold autoimmune hemolytic anemia
 
 - Warm antibody autoimmune hemolytic anemia
 - Alloimmune hemolytic anemia
- Hemolytic disease of the newborn (HDN)
- Rh disease (Rh D)
 - ABO hemolytic disease of the newborn
 - Anti-Kell hemolytic disease of the newborn
 - Rhesus c hemolytic disease of the newborn
 - Rhesus E hemolytic disease of the newborn
 - Other blood group incompatibility (RhC, Rhe, Kid, Duffy, MN, P and others)
 
 
 - Hemolytic disease of the newborn (HDN)
 - Drug induced immune mediated hemolytic anemia
- Penicillin (high dose)
 - Methyldopa
 
 
 - Autoimmune hemolytic anemia
 - Hemoglobinopathies (where these is an unstable or crystalline hemoglobin)
 - Paroxysmal nocturnal hemoglobinuria (rare acquired clonal disorder of red blood cell surface proteins)
 - Direct physical damage to RBCs
- Microangiopathic hemolytic anemia
 - Secondary to artificial heart valve(s)
 
 
 - Aplastic anemia
- Fanconi anemia
 - Diamond–Blackfan anemia (inherited pure red cell aplasia)
 - Acquired pure red cell aplasia
 
 
 - Decreased numbers of cells
- Myelodysplastic syndrome
 - Myelofibrosis
 - Neutropenia (decrease in the number of neutrophils)
 - Agranulocytosis
 - Glanzmann's thrombasthenia
 - Thrombocytopenia (decrease in the number of platelets)
 
 - Myeloproliferative disorders (Increased numbers of cells)
- Polycythemia vera (increase in the number of cells in general)
 - Erythrocytosis (increase in the number of red blood cells)
 - Leukocytosis (increase in the number of white blood cells)
 - Thrombocytosis (increase in the number of platelets)
 - Myeloproliferative disorder
 - Transient myeloproliferative disease
 
 - Coagulopathies (disorders of bleeding and coagulation)
- Thrombocytosis
 - Recurrent thrombosis
 - Disseminated intravascular coagulation
 - Disorders of clotting proteins
 - Disorders of platelets
 
 
Hematological malignancies
- Hematological malignancies
- Lymphomas
- Hodgkin's disease
 - Non-Hodgkin's lymphoma {includes the next five entries}
 
 - Myelomas
 - Leukemias increased WBC
- Acute lymphocytic leukemia (ALL)
 - Chronic lymphocytic leukemia (CLL){now included in theCLL/SCLL type NHL}
 - Acute myelogenous leukemia (AML)
 - Acute megakaryoblastic leukemia (AMKL), a sub-type of acute myelogenous leukemia
 - Chronic Idiopathic Myelofibrosis (MF)
 - Chronic myelogenous leukemia (CML)
 - T-cell prolymphocytic leukemia (T-PLL)
 - B-cell prolymphocytic leukemia (B-PLL)
 - Chronic neutrophilic leukemia (CNL)
 - Hairy cell leukemia (HCL)
 - T-cell large granular lymphocyte leukemia (T-LGL)
 - Aggressive NK-cell leukemia
 
 
 - Lymphomas
 
Miscellaneous
Hematological changes secondary to non-hematological disorders
References
External links
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