Inosine pranobex
 Chemical structures of the three components of inosine pranobex (from top to bottom: inosine, acedoben and dimethylamino isopropanol) | |
| Combination of | |
|---|---|
| Inosine | Immunostimulant |
| Dimethylaminoisopropanol | Immunostimulant |
| Acedoben | Immunostimulant |
| Clinical data | |
| Trade names | Imunovir, Delimmun, Isoprinosine |
| Other names | Methisoprinol |
| AHFS/Drugs.com | https://www.drugs.com/international/isoprinosine-500mg.html |
| Routes of administration | Oral |
| ATC code | |
| Legal status | |
| Legal status |
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| Identifiers | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ECHA InfoCard | 100.048.313 |
Inosine pranobex (BAN; also known as inosine acedoben dimepranol (INN) or methisoprinol) is an antiviral drug that is a combination of inosine and dimepranol acedoben (a salt of acetamidobenzoic acid and dimethylaminoisopropanol) in a ratio of 1 to 3. Inosine pranobex has no effect on viral particles itself. Instead, it acts as an immunostimulant, an analog of thymus hormones.[1]
Inosine pranobex has been used in SSPE, herpes simplex virus, human papillomavirus, HIV, influenza virus, and airway virus infections, cytomegalovirus, and Epstein-Barr virus infections.[2] The effect on SSPE is unclear, it is not a cure for it.[3]
References
- ↑ "Inosine Pranobex". American Cancer Society. Archived from the original on 23 August 2010. Retrieved 31 July 2013.
- ↑ Hashimoto K, Hosoya M (January 2021). "Advances in Antiviral Therapy for Subacute Sclerosing Panencephalitis". Molecules. 26 (2): 427. doi:10.3390/molecules26020427. PMC 7830519. PMID 33467470.
- ↑ Rocke, Zoe; Belyayeva, Mariya (2023), "Subacute Sclerosing Panencephalitis", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 32809508, retrieved 2024-01-19
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