Singles
2010 Roma Open
Champion	Federico del Bonis
Runner-up	Florian Mayer
Score	6–4, 6–3

Daniel Köllerer was the defender of championship title, however lost to Federico del Bonis in the quarterfinals.
del Bonis won in the final 6–4, 6–3, against Florian Mayer.

Seeds

Draw

Finals

	Semifinals							Final
	1/WC	Florian Mayer	6	7
	7	Rubén Ramírez Hidalgo	4	60
								1/WC	Florian Mayer	4	3
									Federico del Bonis	6	6
		Federico del Bonis	6	7
	5	Rui Machado	3	5

Top half

	First round							Second round							Quarterfinals							Semifinals
	1/WC	F Mayer	7	6
		I Minář	60	3				1/WC	F Mayer	6	6
	Q	A Arnaboldi	3	6	6				A Arnaboldi	2	3
	LL	G Naso	6	3	4										1/WC	F Mayer	4	6	6
	SE	J Huta Galung	2	4												A Ungur	6	4	2
		D Guez	6	6					D Guez	6	4	63
		A Ungur	7	6					A Ungur	1	6	7
	LL	L Ouahab	67	4																		1/WC	F Mayer	6	7
	LL	A Smirnov	4	1																		7	R Ramírez Hidalgo	4	60
		F Volandri	6	6					F Volandri	6	3	6
		J Hernych	4	63					M Kližan	4	6	1
		M Kližan	6	7												F Volandri	4	4
	Q	R Eitzinger	4	3											7	R Ramírez Hidalgo	6	6
		V Millot	6	6					V Millot	2	0
		Y Schukin	2	3				7	R Ramírez Hidalgo	6	6
	7	R Ramírez Hidalgo	6	6

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	6	F Gil	6	6
	Q	A di Mauro	1	4				6	F Gil	6	1	4
		F del Bonis	7	6					F del Bonis	3	6	6
		JP Brzezicki	65	2												F del Bonis	6	6
		I Dodig	2	3											3	D Köllerer	2	3
		A Veić	6	6					A Veić	1	2
		L Rosol	0	3				3	D Köllerer	6	6
	3	D Köllerer	6	6																			F del Bonis	6	7
	5	R Machado	6	7																		5	R Machado	3	5
	WC	M Trevisan	3	61				5	R Machado	4	6	7
		J Reister	4	4				WC	M Ančić	6	4	5
	WC	M Ančić	6	6											5	R Machado	6	6
	Q	D Bracciali	6	6											2	D Brands	1	3
	LL	F Aldi	3	4				Q	D Bracciali	6	64	2
		J Vaněk	3	1				2	D Brands	4	7	6
	2	D Brands	6	6

References

• Qualifying Singles
• Main Draw