Singles
2016 Karshi Challenger
Champion	Marko Tepavac
Runner-up	Dudi Sela
Score	2–6, 6–3, 7–6(7–4)

Teymuraz Gabashvili was the defending champion but chose not to participate.

Marko Tepavac won the title after defeating Dudi Sela 2–6, 6–3, 7–6^(7–4) in the final.

Seeds

Draw

Finals

	Semifinals							Final
	1	Dudi Sela	6	6
	3	Radu Albot	4	4
								1	Dudi Sela	6	3	64
									Marko Tepavac	2	6	77
		Ilya Ivashka	4	6	5
		Marko Tepavac	6	3	7

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	D Sela	6	2
	Q	S Betov	1	1r				1	D Sela	6	6
	WC	Pavel Tsoy	1	3					N Milojević	1	2
		N Milojević	6	6											1	D Sela	65	77	6
		A Velotti	6	6											7	D Popko	77	63	4
	Q	D Matsukevich	1	4					A Velotti	6	5	4
	Q	Francesco Vilardo	3	6	64			7	D Popko	4	7	6
	7	D Popko	6	1	77																	1	D Sela	6	6
	3	R Albot	77	6																		3	R Albot	4	4
	WC	S Fayziev	63	4				3	R Albot	6	6
		C Zampieri	2	64					N Barrientos	0	1
		N Barrientos	6	77											3	R Albot	77	2	6
		L Harris	7	3	3											M Dubarenco	62	6	0
		M Dubarenco	5	6	6				M Dubarenco	6	6
		A Bossel	4	6	3			8	A Karatsev	1	2
	8	A Karatsev	6	4	6

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	6	D Molchanov	67	2
	Q	R Muzaev	79	6				Q	R Muzaev	1	4
		S Diez	6	79					S Diez	6	6
		S Griekspoor	2	67												S Diez	3	1
	WC	T Ismailov	5	4												I Ivashka	6	6
		I Ivashka	7	6					I Ivashka	6	3	6
		E López-Pérez	3	6	3			4	A Nedovyesov	3	6	2
	4	A Nedovyesov	6	4	6																		I Ivashka	4	6	5
	5	A Weintraub	4	2																			M Tepavac	6	3	7
		A Bega	6	6					A Bega	5	4
		T-h Yang	3	1					M Tepavac	7	6
		M Tepavac	6	6												M Tepavac	77	6
	WC	Shonigmatjon Shofayziyev	78	2	62										2	K Khachanov	65	4
	LL	S Barry	66	6	77			LL	S Barry	1	4
		A Metreveli	2	2				2	K Khachanov	6	6
	2	K Khachanov	6	6

References

• Main Draw
• Qualifying Draw