| Men's singles | |
|---|---|
| 2021 Mutua Madrid Open | |
| Champion | |
| Runner-up | |
| Score | 6–7(8–10), 6–4, 6–3 | 
| Draw | 56 (8 Q / 4 WC ) | 
| Seeds | 16 | 
Alexander Zverev defeated Matteo Berrettini in the final, 6–7(8–10), 6–4, 6–3 to win the men's singles tennis title at the 2021 Madrid Open. It was Zverev's fourth Masters 1000 title, his first since Madrid 2018, and his 15th career ATP Tour singles title overall. Berrettini was in contention to become the second Italian to be a Masters 1000 champion.[1]
Novak Djokovic was the reigning champion from when the tournament was last held in 2019, but did not participate.[2]
Following the third-round eliminations of Daniil Medvedev and Stefanos Tsitsipas, respectively, a maiden Masters 1000 singles finalist from the bottom half of the draw was guaranteed; Berrettini went on to become that player.[3][4]
Seeds
The top eight seeds received a bye into the second round.
- 1.  
 Rafael Nadal (quarterfinals) - 2.  
 Daniil Medvedev (third round) - 3.  
 Dominic Thiem (semifinals) - 4.  
 Stefanos Tsitsipas (third round) - 5.  
 Alexander Zverev (champion) - 6.  
 Andrey Rublev (third round) - 7.  
 Diego Schwartzman (second round) - 8.  
 Matteo Berrettini (final) 
- 9.  
 Roberto Bautista Agut (second round) - 10.  
 Pablo Carreño Busta (first round) - 11.  
 Denis Shapovalov (second round) - 12.  
 Hubert Hurkacz (first round) - 13.  
 Grigor Dimitrov (first round) - 14.  
 Jannik Sinner (second round) - 15.  
 Félix Auger-Aliassime (first round) - 16.  
 Cristian Garín (quarterfinals) 
Click on the seed number of a player to go to their draw section.
Draw
Key
- Q = Qualifier
 - WC = Wild card
 - LL = Lucky loser
 - Alt = Alternate
 - SE = Special exempt
 - PR = Protected ranking
 - ITF = ITF entry
 - JE = Junior exempt
 - w/o = Walkover
 - r = Retired
 - d = Defaulted
 - SR = Special ranking
 
Finals
| Quarterfinals | Semifinals | Final | ||||||||||||||||||
| 1 | 4 | 4 | ||||||||||||||||||
| 5 | 6 | 6 | ||||||||||||||||||
| 5 | 6 | 6 | ||||||||||||||||||
| 3 | 3 | 4 | ||||||||||||||||||
| 3 | 3 | 6 | 6 | |||||||||||||||||
| 6 | 3 | 4 | ||||||||||||||||||
| 5 | 68 | 6 | 6 | |||||||||||||||||
| 8 | 710 | 4 | 3 | |||||||||||||||||
| 5 | 1 | |||||||||||||||||||
| 7 | 6 | |||||||||||||||||||
| 4 | 4 | |||||||||||||||||||
| 8 | 6 | 6 | ||||||||||||||||||
| 8 | 5 | 6 | 6 | |||||||||||||||||
| 16 | 7 | 3 | 0 | |||||||||||||||||
Top half
Section 1
| First round | Second round | Third round | Quarterfinals | ||||||||||||||||||||||||
| 1 | 6 | 6 | |||||||||||||||||||||||||
| 4 | 0 | WC | 1 | 2 | |||||||||||||||||||||||
| WC | 6 | 6 | 1 | 6 | 6 | ||||||||||||||||||||||
| Q | 6 | 77 | Q | 3 | 3 | ||||||||||||||||||||||
| 3 | 64 | Q | 77 | 6 | |||||||||||||||||||||||
| 2 | 4r | 14 | 65 | 2 | |||||||||||||||||||||||
| 14 | 6 | 4 | 1 | 4 | 4 | ||||||||||||||||||||||
| 12 | 7 | 67 | 3 | 5 | 6 | 6 | |||||||||||||||||||||
| 5 | 79 | 6 | 77 | 2 | 3 | ||||||||||||||||||||||
| 66 | 79 | 2 | 65 | 6 | 6 | ||||||||||||||||||||||
| 78 | 67 | 6 | 3 | 63 | |||||||||||||||||||||||
| 78 | 2 | 2 | 5 | 6 | 77 | ||||||||||||||||||||||
| 66 | 6 | 6 | 3 | 2 | |||||||||||||||||||||||
| 5 | 6 | 6 | |||||||||||||||||||||||||
Section 2
| First round | Second round | Third round | Quarterfinals | ||||||||||||||||||||||||
| 3 | 6 | 6 | |||||||||||||||||||||||||
| Q | 710 | 64 | 5 | Q | 1 | 3 | |||||||||||||||||||||
| Q | 68 | 77 | 7 | 3 | 79 | 6 | |||||||||||||||||||||
| 4 | 7 | 6 | 67 | 4 | |||||||||||||||||||||||
| WC | 6 | 5 | 1 | 6 | 3 | ||||||||||||||||||||||
| 6 | 3 | 77 | 2 | 0r | |||||||||||||||||||||||
| 13 | 3 | 6 | 65 | 3 | 3 | 6 | 6 | ||||||||||||||||||||
| 9 | 6 | 63 | 7 | 6 | 3 | 4 | |||||||||||||||||||||
| Q | 2 | 77 | 5 | 9 | 4 | 77 | 66 | ||||||||||||||||||||
| 6 | 78 | 6 | 64 | 78 | |||||||||||||||||||||||
| 4 | 66 | 77 | 3 | 77 | |||||||||||||||||||||||
| WC | 4 | 5 | 6 | 64 | 6 | 64 | |||||||||||||||||||||
| 6 | 7 | 77 | 3 | 4 | |||||||||||||||||||||||
| 6 | 65 | 6 | 6 | ||||||||||||||||||||||||
Bottom half
Section 3
| First round | Second round | Third round | Quarterfinals | ||||||||||||||||||||||||
| 7 | 6 | 4 | 1 | ||||||||||||||||||||||||
| 5 | 4 | 2 | 6 | 6 | |||||||||||||||||||||||
| 7 | 6 | 4 | 3 | ||||||||||||||||||||||||
| 65 | 3 | 6 | 6 | ||||||||||||||||||||||||
| 77 | 6 | 6 | 5 | 6 | |||||||||||||||||||||||
| 1 | 3 | 11 | 4 | 7 | 4 | ||||||||||||||||||||||
| 11 | 6 | 6 | 5 | 1 | |||||||||||||||||||||||
| 15 | 1 | 4 | 7 | 6 | |||||||||||||||||||||||
| 6 | 6 | 6 | 6 | ||||||||||||||||||||||||
| LL | 6 | 6 | LL | 1 | 2 | ||||||||||||||||||||||
| 2 | 4 | 77 | 6 | ||||||||||||||||||||||||
| 4 | 5 | 4 | 64 | 4 | |||||||||||||||||||||||
| 6 | 7 | 1 | 2 | ||||||||||||||||||||||||
| 4 | 6 | 6 | |||||||||||||||||||||||||
Section 4
| First round | Second round | Third round | Quarterfinals | ||||||||||||||||||||||||
| 8 | 6 | 6 | |||||||||||||||||||||||||
| Q | 64 | 6 | 3 | 3 | 4 | ||||||||||||||||||||||
| 77 | 2 | 6 | 8 | 77 | 6 | ||||||||||||||||||||||
| 5 | 7 | 4 | Q | 64 | 4 | ||||||||||||||||||||||
| 7 | 5 | 6 | 65 | 3 | |||||||||||||||||||||||
| Q | 3 | 6 | 6 | Q | 77 | 6 | |||||||||||||||||||||
| 10 | 6 | 4 | 3 | 8 | 5 | 6 | 6 | ||||||||||||||||||||
| 16 | 6 | 6 | 16 | 7 | 3 | 0 | |||||||||||||||||||||
| WC | 1 | 4 | 16 | 6 | 6 | ||||||||||||||||||||||
| 6 | 6 | 3 | 4 | ||||||||||||||||||||||||
| 4 | 4 | 16 | 6 | 62 | 6 | ||||||||||||||||||||||
| Q | 77 | 64 | 64 | 2 | 4 | 77 | 1 | ||||||||||||||||||||
| 65 | 77 | 77 | 6 | 4 | 2 | ||||||||||||||||||||||
| 2 | 4 | 6 | 6 | ||||||||||||||||||||||||
Qualifying
Seeds
 Laslo Đere (first round)
 Yoshihito Nishioka (qualifying competition, retired, lucky loser)
 Jordan Thompson (first round)
 Tennys Sandgren (first round)
 Frances Tiafoe (first round)
 Sebastian Korda (first round)
 Stefano Travaglia (qualifying competition)
 Emil Ruusuvuori (first round)
 Egor Gerasimov (first round)
 Alexei Popyrin (qualified)
 Thiago Monteiro (first round)
 Federico Delbonis (qualified)
 Pablo Andújar (qualified)
 Radu Albot (first round)
Qualifiers
Lucky loser
Qualifying draw
First qualifier
| First round | Qualifying competition | ||||||||||||
| 1 | 3 | 6 | 2 | ||||||||||
| 6 | 3 | 6 | |||||||||||
| 4 | 4 | ||||||||||||
| 12 | 6 | 6 | |||||||||||
| WC | 65 | 65 | |||||||||||
| 12 | 77 | 77 | |||||||||||
Second qualifier
| First round | Qualifying competition | ||||||||||||
| 2 | 6 | 6 | |||||||||||
| 4 | 4 | ||||||||||||
| 2 | 77 | 4 | 0r | ||||||||||
| 64 | 6 | 0 | |||||||||||
| 6 | 612 | 77 | |||||||||||
| 11 | 4 | 714 | 64 | ||||||||||
Third qualifier
| First round | Qualifying competition | ||||||||||||
| 3 | 6 | 66 | 2 | ||||||||||
| WC | 3 | 78 | 6 | ||||||||||
| WC | 6 | 6 | |||||||||||
| 4 | 2 | ||||||||||||
| 6 | 6 | ||||||||||||
| 14 | 3 | 4 | |||||||||||
Fourth qualifier
| First round | Qualifying competition | ||||||||||||
| 4 | 3 | 2 | |||||||||||
| 6 | 6 | ||||||||||||
| 77 | 6 | ||||||||||||
| 64 | 4 | ||||||||||||
| 6 | 6 | ||||||||||||
| 9 | 4 | 3 | |||||||||||
Fifth qualifier
| First round | Qualifying competition | ||||||||||||
| 5 | 64 | 2 | |||||||||||
| 77 | 6 | ||||||||||||
| 4 | 6 | 6 | |||||||||||
| 6 | 0 | 3 | |||||||||||
| 6 | 6 | ||||||||||||
| 8 | 2 | 3 | |||||||||||
Sixth qualifier
| First round | Qualifying competition | ||||||||||||
| 6 | 63 | 4 | |||||||||||
| WC | 77 | 6 | |||||||||||
| WC | 5 | 60 | |||||||||||
| 10 | 7 | 77 | |||||||||||
| 77 | 4 | 3 | |||||||||||
| 10 | 64 | 6 | 6 | ||||||||||
Seventh qualifier
| First round | Qualifying competition | ||||||||||||
| 7 | 5 | 6 | 7 | ||||||||||
| WC | 7 | 1 | 5 | ||||||||||
| 7 | 77 | 5 | 3 | ||||||||||
| 13 | 63 | 7 | 6 | ||||||||||
| 3 | 4 | ||||||||||||
| 13 | 6 | 6 | |||||||||||
ATP singles main-draw entrants
Seeds
The following are the seeded players. Seedings are based on ATP rankings as of 26 April 2021. Rankings and points before are as of 3 May 2021.
| Seed | Rank | Player | Points before | Points defending | Points won | Points after | Status | 
|---|---|---|---|---|---|---|---|
| 1 | 2 | 9,810 | 360 | 180 | 9,630 | Quarterfinals lost to  | |
| 2 | 3 | 9,700 | 10 | 90 | 9,780 | Third round lost to  | |
| 3 | 4 | 8,365 | 360 | 360 | 8,365 | Semifinals lost to  | |
| 4 | 5 | 7,910 | 390 | 90 | 7,610 | Third round lost to  | |
| 5 | 6 | 6,125 | 180 | 1,000 | 6,945 | Champion, defeated  | |
| 6 | 8 | 6,000 | 90 | 90 | 6,000 | Third round lost to  | |
| 7 | 9 | 3,765 | 67 | 45 | 3,743 | Second round lost to  | |
| 8 | 10 | 3,493 | 45 | 600 | 4,048 | Runner-up, lost to  | |
| 9 | 11 | 3,090 | 10 | 45 | 3,125 | Second round lost to  | |
| 10 | 12 | 3,015 | 10 | 10 | 3,015 | First round lost to  | |
| 11 | 14 | 2,820 | 10 | 45 | 2,855 | Second round lost to  | |
| 12 | 16 | 2,600 | 67 | 10 | 2,543 | First round lost to  | |
| 13 | 17 | 2,576 | 10 | 10 | 2,576 | First round lost to  | |
| 14 | 18 | 2,524 | 24 | 45 | 2,545 | Second round lost to  | |
| 15 | 20 | 2,418 | 32 | 10 | 2,396 | First round lost to  | |
| 16 | 22 | 2,215 | 45 | 180 | 2,350 | Quarterfinals lost to  | 
Other entrants
The following players received wildcards into the main draw:
The following players received entry from the qualifying draw:
 Pablo Andújar
 Marco Cecchinato
 Federico Delbonis
 Marcos Giron
 Pierre-Hugues Herbert
 Alexei Popyrin
 Carlos Taberner
The following player received entry as a lucky loser:
Withdrawals
- Before the tournament
 
 Marin Čilić → replaced by 
 Tommy Paul
 Borna Ćorić → replaced by 
 Jérémy Chardy
 Novak Djokovic → replaced by 
 Alejandro Davidovich Fokina
 Roger Federer → replaced by 
 Miomir Kecmanović
 David Goffin → replaced by 
 Lloyd Harris
 Gaël Monfils → replaced by 
 Guido Pella
 Milos Raonic → replaced by 
 Yoshihito Nishioka
 Lorenzo Sonego → replaced by 
 Dominik Koepfer
 Stan Wawrinka → replaced by 
 Albert Ramos Viñolas
Retirements
References
- ↑ "Zverev Completes Magical Madrid Run". Association of Tennis Professionals. 9 May 2021. Archived from the original on 10 May 2021. Retrieved 23 April 2022.
 - ↑ "Djokovic Withdraws From Madrid". Association of Tennis Professionals. 28 April 2021. Archived from the original on 11 May 2021. Retrieved 3 May 2021.
 - ↑ "Berrettini Bests Garin To Reach Madrid Semi-finals". Association of Tennis Professionals. 7 May 2021. Archived from the original on 7 June 2021. Retrieved 23 April 2022.
 - ↑ "Berrettini, Ruud Battle For Second Madrid Final Spot". Association of Tennis Professionals. 7 May 2021. Archived from the original on 16 April 2022. Retrieved 23 April 2022.