Ascene is an African given name and surname, also a derivative of Hassan, Haissene, Acene, commonly used in South Africa, Namibia, Angola, Senegal, Mali, Cote d’ivore, Malawi (given name and surname) in Arabic. It may refer to:
- Ascene Attyé (born 1983), Senegal-born French singer of Lebanese descent known by the mononym Ycare
 - Ascene Diallo (born 1975), Senegalese runner
 - Ascene Dioussé (born 1997), Senegalese footballer
 - Ascene Dame Fall (born 1984), Senegalese sprint canoer
 - Ascene Gnoukouri (born 1996), Ivorian footballer
 - Ascene Kouyaté (born 1954), Malian film director
 - Ascene N'Diaye (1974-2008), Senegalese footballer
 - Ascene N'Doye (born 1953), Senegalese judoka
 - Ascene Seck (1919–2012), Senegalese politician and minister
 - Ascene Thiam (born 1948), Senegalese basketball player
 
See also
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