François Dominique may refer to:
- François Dominique de Barberie de Saint-Contest
- François Dominique de Reynaud, Comte de Montlosier, French politician
- François Dominique (writer), French writer and translator
Persons with the given name
- François Dominique Barreau de Chefdeville, French architect
- François-Dominique Toussaint Louverture, leader of the Haitian Rebellion
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