Gleeson may refer to:
- Gleeson, Arizona, an American ghost town
 - Gleeson College, Adelaide, Australia, a Catholic secondary school
 - Gleeson (surname), people with the surname
 - Gleeson Hedge, a character in mythology novels by Rick Riordan
 
See also
- Gleeson gunfight (1917), one of the last gunfights of the American Old West
 - Gleason (disambiguation)
 
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