Fictional entities

• Iris (American Horror Story), an American Horror Story: Hotel character
• Iris (Fire Force), a character in the manga series Fire Force
• Iris (Mega Man), a Mega Man X4 character
  • Iris, a Mega Man Battle Network character
• Iris (Pokémon)
  • Iris (Pokémon anime)
• Iris, a Trolls: The Beat Goes On! character
• Sorceress Iris, a Magicians of Xanth character
• Iris, a kaiju character in Gamera 3: The Revenge of Iris
• Iris, a LoliRock character
• Iris, a Lufia II: Rise of the Sinistrals (1995) character
• Iris, a Phoenix Wright: Ace Attorney − Trials and Tribulations character
• Iris, a Ruby Gloom character
• Iris, a Taxi Driver (1976) character
• The Iris, the antagonist in Gemini Home Entertainment web series
• Iris Donnelly Garrison, a fictional character in the American soap opera Love is a Many Splendored Thing
• Iris Irine, a Ragnarok character
• Iris Sagan, in AI: The Somnium Files
• Iris West, a DC Comics character

Film, television, and theatre

Music

Periodicals

• El Iris, a Mexican periodical published in 1826
• Sheffield Iris, an early English newspaper
• IRIS Magazine, an Irish republican magazine

Other media

• Iris (game), a Halo 3 online promotion
• Irises (painting), by Vincent Van Gogh
• Iris, Messenger of the Gods, a sculpture by Auguste Rodin

Charitable organizations

• IRIS (radio reading service), provided by Vision Australia Radio
• Iris Fund for Prevention of Blindness, a British charity, now part of Fight for Sight
• International Resources for the Improvement of Sight, a multi-national charity

Research groups

• IRIS Consortium, a seismology research project
• IRIS Research, an Australian economic, community and industry research organisation
• Information Systems Research in Scandinavia, a non-profit organization in Scandinavia
• Institute for Research in Information and Scholarship, a Brown University program

Other organizations

• Iris Associates, an American software company, developer of Lotus Notes
• Iris Capital, a venture capital firm primarily active in Europe
• Iris Clert Gallery, a former art gallery in Paris
• Iris Ohyama, a Japanese manufacturing company
• Denso Iris, a basketball team based in Kariya, Aichi

United States

• Iris, West Virginia, a community in the United States
• Iris Avenue station, on the San Diego Trolley
• Iris Falls, a waterfall in Wyoming

Elsewhere

• Iris, Cluj-Napoca, a district in Romania
• Iris, Prince Edward Island, a community in Canada
• Irıs, Tatarstan, a place in Russia
• Iris Bay, in South Georgia, British Overseas Territory
• Iris Bay (Dubai), a tower in the United Arab Emirates
• Glen Iris (disambiguation), several places
• River Iris, now Yeşilırmak River, a river in northern Turkey, called Iris in classical Greek
• IRIS Mist, a tower to be built in Dubai Maritime City, United Arab Emirates

Astronomy and spaceflight

• IRIS (astronomical software), an image processing application
• Iris (transponder), designed for use in cubesats
• 7 Iris, an asteroid
• Infrared interferometer spectrometer and radiometer, an instrument used in the Voyager space program
• Interface Region Imaging Spectrograph, a space probe to observe the Sun
• Iris Nebula, a reflection nebula and Caldwell object in the constellation Cepheus
• International Radiation Investigation Satellite, an early satellite to study radiation in space
• Internet Routing in Space, a space-capable IP router

Biology and medicine

• Iris (anatomy), part of the eye
• Iris (insect), a genus of praying mantis
• Iris (plant), a genus of flowering plants
• Iris (psychedelic), a psychedelic drug
• Iris glossy-starling, the emerald starling (Lamprotornis iris)
• Immune reconstitution inflammatory syndrome, a complication of HIV treatment

Computing

Other uses in science and technology

• Iris (diaphragm), a mechanical device in optical systems
• Tropical Storm Iris (disambiguation), three tropical cyclones in the Atlantic Ocean
• IRIS (jamming device), an Estonian weapon
• IRIS Consortium, a seismology research project
• Institute for Research in Information and Scholarship, a Brown University program
• Internal rotary inspection system, a pipe testing method
• International Reactor Innovative and Secure, a nuclear reactor design
• IRIS (French: Îlots regroupés pour l'information statistique), aggregated units for statistical information in French census mapping

Aircraft and missiles

• Abraham Iris, a 1930s French touring airplane
• Blackburn Iris, a 1920s British biplane flying boat
• IRIS-T, a German air-to-air missile
• Shahab-4 or IRIS, an Iranian liquid propelled missile

Automobiles

• Iris (car), a British car brand manufactured 1906–1925
• Desert Iris, a Jordanian 4x4 strategic auxiliary vehicle
• Tata Magic Iris, an Indian microvan
• Wallyscar Iris, a Tunisian mini SUV

Engines

• IRIS engine, a design for a type of internal combustion engine
• de Havilland Iris, a British four-cylinder, liquid-cooled, horizontally opposed aero engine

Rail transportation

• Iris (train), an international express train in Europe
• International Railway Industry Standard; see Union des Industries Ferroviaires Européennes

Watercraft

• List of ships named Iris, for any of several ships by that name
• French ship Iris, the name of several vessels
• HMS Iris, the name of several Royal Navy ships
• MV Royal Iris, a ferry operating until 1991
• USS Iris, the name of several U.S. Navy ships
• MV Royal Iris of the Mersey, a ferry operating since 2001
• IRIS, the prefix for Iranian naval vessels since 1979; see List of current ships of the Islamic Republic of Iran Navy