Marioni is a surname that may refer to:
- Bruno Marioni (born Bruno Giménez, 1975), retired Argentine striker
- Dante Marioni (born 1964), American glass artist
- John Marioni, computational biologist, Head of Research at the European Bioinformatics Institute
- Paul Marioni (born 1941), American artist
- Tom Marioni (born 1937), American artist and educator
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