Mary Brown or Browne may refer to:
- Mary Brown, alias for Typhoid Mary (1869–1938), first identified asymptomatic carrier of typhoid fever in the United States
 - Mary Brown (author) (1929–1999), British fantasy and science fiction author
 - Mary Brown (Michigan politician) (1935–2021), American politician and educator
 - Mary Brown (nurse) (1840–1936), nurse and soldier in the American Civil War
 - Mary Brown Bullock (born in 1940s), American academic specializing in Chinese history
 - Mary Browne (1891–1971), American tennis player
 - Mary Browne, Countess of Southampton (1552–1603), English peer
 - Mary Ann Browne (1812–1845), English poet and writer of musical scores
 - Mary Ann Day Brown (1816–1884), wife of abolitionist John Brown
 - Mary Annora Brown (1899–1987), Canadian artist
 - Mary Babnik Brown (1907–1991), American who donated her hair for using as bombsight crosshairs
 - Mary Bonaventure Browne (17th century), Irish abbess and historian
 - Mary Elizabeth Brown (1862–1952), first female graduate of the University of Sydney
 - Mary Louise Brown (1868–1927), first African-American woman to receive a wartime medical commission
 - Mary Ward Brown (1917–2013), American short-story writer and memoirist
 - Mary Browne (courtier) (1593–1692), English aristocrat
 - Mary Elizabeth Adams Brown (1842–1918), American writer, collector, and curator of musical instruments
 - Mary Brown (songwriter), American singer and songwriter
 - "Mary Brown", a song by Irving Berlin
 
See also
- Mary Brown's (founded in 1969), restaurant chain in Canada
 
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