PDS can refer to:
Entertainment
- Partially Deceased Syndrome, a fictional condition in BBC show In the Flesh
 - Panzer Dragoon Saga, a 1998 video game
 
Computing
- Partitioned data sets, IBM
 - Passive data structure, another term for record
 - Processor Direct Slot, in some old Macintosh computers
 - Personal data service, services to let individuals manage their own personal data by themselves
 - Protective distribution system, a safeguarded telecommunication system
 - Microsoft BASIC Professional Development System (PDS), a superset of QuickBASIC
 - Paradox Development Studios, a game developer subsidiary of Paradox Interactive
 
Medical
- Paroxysmal depolarizing shift, a pre-seizure interictal neuronal EEG spike in epilepsy.
 - Pigment dispersion syndrome, an affliction of the eye
 - Polydioxanone, a type of absorbable suture
 - Pleomorphic dermal sarcoma, a form of histiocytoma
 
Political parties
- Party of Democratic Socialism (Partei des Demokratischen Sozialismus), a defunct political party of Germany
 - Social Democracy Party of Albania
 - Party of Democratic Socialism (India)
 - Party of the Sicilians
 - Progressive Democrats, a defunct political party of Ireland
 - Democratic Party of the Left (Partito Democratico della Sinistra), a defunct political party of Italy
 - Senegalese Democratic Party (Parti Démocratique Sénégalais), a political party of Senegal
 - Sudanese Democratic Party (Parti Démocratique Soudanais), a defunct political party of Sudan
 - Democratic Social Party (Partido Democrático Social), a defunct political party of Brazil
 - Prosperous Peace Party (Partai Damai Sejahtera), a political party of Indonesia
 - Parti de la Democratie Socialiste, a defunct provincial political party of Quebec, Canada
 
Schools
- Princeton Day School, New Jersey, US
 - Peabody Demonstration School, former school in Nashville, Tennessee, US
 - Presbyterian Day School, Memphis, Tennessee, US
 - Providence Day School, Charlotte, North Carolina, US
 - Patumwan Demonstration School, Srinakharinwirot University, Bangkok, Thailand
 
Scientific
- Photothermal deflection spectroscopy
 - Planetary Data System, a NASA data archive system
 - Polydioxanone, a synthetic polymer
 - 15-Cis-phytoene desaturase, an enzyme
 - Poincaré dodecahedral space
 
Other
- Particularly dangerous situation, special emphasis phrase in weather bulletins from the National Weather Service
 - Piedras Negras International Airport, IATA code PDS
 - Precision Drill Squad, a skilled military performance of Singapore
 - Product design specification
 - Public distribution system, Indian food distribution system
 - The Philip DeFranco Show, on YouTube
 - Permanent Duty Station, in the United States military forces (see temporary duty assignment)
 
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