Persis is a feminine given name, meaning "from Persia". Notable people with the name include:
- Persis Drell (born 1955), American physicist
 - Persis Karim (born 1962), American poet, editor, educator
 - Persis Khambatta (1948–1998), Indian actress and model
 - Persis Kirmse (1884–1955), British painter
 - Persis Goodale Thurston Taylor (1821–1906), Hawaiian artist
 - Persis Robertson (1896–1992), American artist
 
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