Seydou is the Francophonic-orthography variant of the Arabic name Sa'id, commonly used in West Africa.
Notable people with the name include:
- Seydou Bouda (born 1958), Burkinabé politician and US Ambassador
 - Mohamed Seydou Dera (born 1986), Côte d'Ivoire footballer
 - Seydou Diarra (1933–), Ivorian political figure, Prime Minister in 2000 and from 2003 to 2005
 - Pape Seydou Diop (born 1979), Senegalese international footballer
 - Seydou Doumbia (born 1987), Ivorian footballer
 - Seydou Badjan Kanté (born 1981), former Ivory Coast-born football defender
 - Seydou Keita (footballer) (born 1980), Malian professional footballer
 - Seydou Keïta (photographer) (1921–2001), self-taught portrait photographer from Bamako
 - Seydou Koné (born 1983), Ivorian professional football player
 - Seydou Badian Kouyaté (born 1928), Malian writer and politician
 - Seydou Njoya (1902–1992), ruled the Bamum people of Cameroon from 1933 to 1992
 - Chris Seydou (1949–1994), Malian fashion designer
 - Mayaki Seydou (born 1949), former Nigerien bantamweight boxer
 - Seydou Traoré (born 1970), former Burkinabé footballer
 
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