Thomas Keane may refer to:
- Tom Keane (1926–2001), American football cornerback
 - Tom Keane, musician, see The Keane Brothers
 - Rory Keane (Thomas Roderick Keane, 1922–2004), Irish footballer
 - Tommy Keane (1968–2012), Irish footballer
 - Thomas E. Keane (1905–1996), American politician
 - Thomas P. Keane (1878–1945), American politician
 
See also
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