Tufa may refer to:
- Tufa, a variety of limestone
 - Tufa, Germanic warrior active in 5th century Italy
 - North Dock Tufa, petrified tufa formation in Sunderland, England
 - Caerwys Tufa, preserved tufa formation in Clwyd, Wales
 - Mono Lake Tufa State Natural Reserve, natural reserve in California, United States
 - Tufa River, a tributary of the Prahova River in Romania
 - Tufa, the founding family of Southern Liang, a state during the Chinese Jin Dynasty
- Tufa Wugu (died 399), founding prince of Southern Liang
 - Tufa Lilugu (died 402), second ruler of Southern Liang
 - Tufa Rutan (365–415), last ruling prince of Southern Liang
 - Princess Tufa (died 423), daughter of Tufa Rutan
 
 - Tufa (Amharic: ቱፋ), a male given name of Ethiopian origin
- Firehiwot Tufa Dado (born 1984), Ethiopian marathon runner
 - Mestawet Tufa (born 1983), Ethiopian long-distance runner
 
 - Tufa, a summer settlement in Çaykara district of Trabzon province, Turkey.
 - Tufa, a fictional clan of fairies in Alex Bledsoe's fantasy novel, The Hum and the Shiver
 
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