List of adverse effects of ribavirin

Temporary visual loss after treatment with ribavirin (and pegylated interferon alfa-2a). Both eyes at admission and 5 years later

List of adverse effects of ribavirin by frequency.[1][2][3]

Very common (>10% frequency)

Common (1-10% frequency)

  • Hemolytic anemia
  • Leukopenia
  • Thrombocytopenia
  • Lymphadenopathy
  • Lymphopenia
  • Hypothyroidism
  • Hyperthyroidism
  • Hyperglycemia
  • Hyperuricemia
  • Hypocalcemia
  • Dehydration
  • Increased appetite
  • Palpitation
  • Tachycardia
  • Hypotension
  • Hypertension
  • Flushing
  • Hepatomegaly
  • Jaundice
  • Hyperbilirubinemia
  • Arthritis
  • Back pain
  • Muscle spasms
  • Pain in extremity
  • Micturition frequency
  • Polyuria
  • Urine abnormality
  • Chest pain
  • Chest discomfort
  • Peripheral edema
  • Malaise
  • Feeling abnormal
  • Thirst
  • Cardiac murmur
  • Neoplasm formation
  • Sexual disturbances (including erectile dysfunction, prostatis, amenorrhea, etc.)
  • Skin disturbances (including acne, eczema, psoriasis, etc.)
  • Gastrointestinal disturbances (including mouth ulcers, indigestion, diarrhea, constipation, etc.)
  • Upper respiratory tract disturbances (including nosebleeds, nasal/sinus congestion, etc.)
  • Visual and hearing disturbances (including tinnitus, blurred vision, etc.)
  • Neurologic disturbances (including memory loss, migraines, incoordination, sensory distortions, etc.)
  • Psychiatric disturbances (including suicidal ideation and psychosis)
  • Infections (including sinusitis, the flu, sepsis, UTIs, etc.)

Uncommon (0.1-1% frequency)

  • Immediately life-threatening psychiatric disturbances, including suicide attempts and hallucinations

Rare (0.01-0.1% frequency)

Very rare (<0.01% frequency)

Unknown frequency

References

  1. ↑ "PRODUCT INFORMATION REBETOL (RIBAVIRIN) CAPSULES" (PDF). TGA eBusiness Services. Merck Sharp & Dohme (Australia) Pty Limited. 29 April 2013. Archived from the original on 16 August 2017. Retrieved 23 February 2014.
  2. ↑ "COPEGUS (RIBAVIRIN) TABLET, FILM COATED [GENENTECH, INC]". DailyMed. Genentech, Inc. February 2013. Archived from the original on 12 October 2012. Retrieved 23 February 2014.
  3. ↑ "Rebetol 200mg hard capsules - Summary of Product Characteristics". Merck Sharp & Dohme Limited. 27 January 2014. Archived from the original on 27 February 2014. Retrieved 23 February 2014.
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