List of medical abbreviations: S
| Abbreviation | Meaning | 
|---|---|
| s̅ | without (s with an overbar) (from Latin sine) | 
| S | sacrum | 
| Sx | symptoms  surgery (though deemed by some as inappropriate)  | 
| S1 | first heart sound | 
| S2 | second heart sound | 
| S3 | third heart sound | 
| S4 | fourth heart sound | 
| S&O | salpingo-oophorectomy | 
| Sb | Scholar batch | 
| SAAG | serum–ascites albumin gradient | 
| SAB | staphylococcal bacteremia  spontaneous abortion (that is, miscarriage)  | 
| SAD | seasonal affective disorder  subacromial decompression  | 
| SAH | subarachnoid hemorrhage | 
| SAM | systolic anterior motion of the mitral valve
 Severe acute malnutrition  | 
| SAN | sinoatrial node | 
| SaO2 | arterial oxygen saturation | 
| SAPS II | simplified acute physiology score | 
| SAPS III | simplified acute physiology score | 
| SAR | seasonal allergic rhinitis sub-acute rehabilitation facility  | 
| Sarc | sarcoidosis | 
| SARS | severe acute respiratory syndrome | 
| SB | small bowel (see small intestine) | 
| SBE | subacute bacterial endocarditis | 
| SBFT | small bowel follow through | 
| SBMA | spinal and bulbar muscular atrophy | 
| SBO | small bowel obstruction | 
| SBP | systolic blood pressure  spontaneous bacterial peritonitis  | 
| SBR | Serum Bilirubin | 
| SBRT | split beam radiation therapy | 
| SC | Spinal Cord or subcutaneous (from Latin subcutis) | 
| SCA | spinocerebellar ataxia | 
| SCAT | sex cord tumor with annular tubes | 
| SCC | squamous cell carcinoma | 
| SCD | sequential compression device  sickle-cell disease sudden cardiac death  | 
| SCI | spinal cord injury | 
| SCID | severe combined immunodeficiency | 
| SCIWORA | spinal cord injury without radiographic abnormality | 
| SCLC | small cell lung cancer | 
| scope | microscope or endoscope | 
| SCT | sacrococcygeal tumor | 
| SCZ | schizophrenia | 
| S.D. | subdermal | 
| SD  σ  | standard deviation | 
| SDH | subdural hematoma | 
| SDTI | suspected deep tissue injury | 
| SE | standard error  side effect  | 
| Sed | sedimentation (rate) (see erythrocyte sedimentation rate) | 
| SEE | syphilis elimination effort | 
| Segs | segmented cells | 
| SEM | standard error of the mean  systolic ejection murmur (see heart murmur)  | 
| SERM | selective estrogen receptor modulator | 
| SERT | serotonin transporter | 
| SFA | superficial femoral artery  serum folic acid  | 
| SGA | small for gestational age | 
| SG cath | Swan–Ganz catheter (see pulmonary artery catheter) | 
| SG | specific gravity (in urinanalysis) | 
| SGB | stellate ganglion block | 
| SGOT | serum glutamic oxaloacetic transaminase | 
| SGPT | serum glutamic pyruvic transaminase | 
| SH  SHx  | social history (personal habits, living situation, job) | 
| SHBG | sex hormone-binding globulin | 
| shob | shortness of breath (see dyspnea) | 
| SHPT | secondary hyperparathyroidism | 
| SHx | surgical history | 
| SI | International System of Units  suicidal ideation seriously ill sacroiliac (joint)  | 
| STAC | Scaffolding theory of cognitive aging | 
| SIADH | syndrome of inappropriate antidiuretic hormone | 
| SICU | surgical intensive care unit | 
| SIBO | small intestinal bacterial overgrowth | 
| SID | semel in die meaning once daily. Used only in veterinary medicine. | 
| SIDS | sudden infant death syndrome | 
| SIL | squamous intraepithelial lesion | 
| SIMV | synchronized intermittent mechanical ventilation | 
| si op. sit | if needed (from Latin si opus sit) | 
| SIRS | systemic inflammatory response syndrome | 
| SIT | stress inoculation training (see posttraumatic stress disorder) | 
| SJS | Stevens–Johnson syndrome | 
| SK | streptokinase | 
| sl | sublingual | 
| SLE | systemic lupus erythematosus | 
| SLEV | St Louis virus | 
| SLL | small lymphocytic lymphoma | 
| SLN | sublingual nitroglycerin | 
| SLN SLNB  | sentinel lymph node biopsy | 
| SLP | speech-language pathologist | 
| SLR | straight leg raise (see Lasègue's sign) | 
| SM | multiple sclerosis (from Latin sclerosis multiplex)  submucosal Skeletal Muscle  | 
| SMA | sequential multiple analysis  superior mesenteric artery spinal muscle atrophy  | 
| SMA-6 | six-channel serum multiple analysis | 
| SMA-7 | serum metabolic assay | 
| SMN | statement of medical necessity | 
| SMS | senior medical student | 
| SMT | spinal manipulative therapy | 
| SMV | superior mesenteric vein | 
| SN | student nurse   skilled nursing  | 
| SNB | sentinel node biopsy (ductal carcinoma) | 
| SNF | skilled nursing facility | 
| SNHL | sensorineural hearing loss | 
| SNP | sodium nitroprusside  single nucleotide polymorphism  | 
| SNRI | serotonin–norepinephrine reuptake inhibitor | 
| SNV | sin nombre virus (the most common type of hantavirus)  single nucleotide variant  | 
| SO | salpingo-oophoritis | 
| SOA | swelling of ankles | 
| SOAP | subjective, objective, assessment, plan (how physicians’ notes may be organized) | 
| SOB | shortness of breath (see dyspnea) | 
| SOBOE | shortness of breath on exertion | 
| SOL | space-occupying lesion | 
| Sol | solution | 
| SOOB | send out of bed  sitting out of bed  | 
| SOP | sterile ophthalmic preparation | 
| SORA | stable on room air | 
| SOS | if needed (from Latin si opus sit) | 
| SP  s/p  | status post; condition after" | 
| SPE | streptococcal pyrogenic exotoxin | 
| Spec | specimen | 
| SPECT | single-photon emission computed tomography | 
| SPEP | serum protein electrophoresis | 
| SPET | single-photon emission tomography | 
| spp. | species, as in bacterial species (e.g. Enterobacteriaceae spp.) | 
| Sp. fl. | spinal fluid (see cerebrospinal fluid) | 
| Sp. gr. | specific gravity | 
| SPS | single point (walking) stick | 
| SQ  sq  | subcutaneous | 
| SR | slow release (see also time release technology (medicine)) Sinus rhythm  | 
| SpO2 | peripheral capillary oxygen saturation | 
| SROM | spontaneous rupture of membranes | 
| SRS | stereotactic radiotherapy  sex reassignment surgery  | 
| SRU | shock resuscitation unit | 
| ss ss  | one-half (ss either with or without a bar over them) (from Latin semis) | 
| SS | hemoglobin SS (HbSS) (see in sickle-cell disease = SS disease)  subserosal Sjogren's Syndrome  | 
| S/S  S/Sx  | signs and symptoms | 
| SSC | secondary sex characteristics | 
| SSE | sterile speculum exam | 
| SSEP | somatosensory evoked potential | 
| SSI | sliding scale insulin | 
| SSKI | potassium iodide solution | 
| SSPE | subacute sclerosing panencephalitis | 
| ssRNA | single-stranded RNA | 
| SSRI | selective serotonin reuptake inhibitor | 
| SSSI | skin and skin structure infection (also referred to as acute bacterial skin and skin structure infection - ABSSSI) | 
| SSSS | staphylococcal scalded skin syndrome | 
| SSS | sick sinus syndrome | 
| ST | sore throat   speech therapy  | 
| Staph. | Staphylococcus | 
| STD | sexually transmitted disease | 
| stat | immediately (from Latin statim) | 
| STEC | Shiga toxin–producing Escherichia coli (another name for enterohemorrhagic E. coli) | 
| STEMI | ST elevation myocardial infarction | 
| STH | somatotropic hormone | 
| STI | sexually transmitted infection  soft tissue injury  | 
| STN | Subthalamic nucleus  soft tissue neck  | 
| STNR | Symmetrical tonic neck reflex | 
| STOP | surgical termination of pregnancy (sometimes suction termination of pregnancy) | 
| Strep.  Strepto.  | Streptococcus | 
| STS | serological test for syphilis  soft tissue sarcoma  | 
| Subq | subcutaneous | 
| SUD | substance use disorder | 
| SUI | stress urinary incontinence | 
| Supp | suppository | 
| SUV | standardized uptake value | 
| Sux | Suxamethonium chloride (Succinylcholine) | 
| SV | seminal vesicle  stroke volume  | 
| SVC | superior vena cava | 
| SVD | spontaneous vaginal delivery  simple vertex delivery  | 
| SVE | sterile vaginal examination | 
| SVG | Saphenous vein graft | 
| SVI | systemic viral infection | 
| SVN | small volume nebulizer | 
| SVR | systemic vascular resistance | 
| SVT | supraventricular tachycardia | 
| SW | Sturge–Weber syndrome | 
| Sx | symptoms | 
| SXA | single-energy X-ray absorptiometer | 
| SXR | skull x-ray | 
| Sz | seizure | 
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