GPR62

GPR62
Identifiers
Aliases	GPR62, GPCR8, KPG_005, G protein-coupled receptor 62
External IDs	OMIM: 606917 MGI: 3525078 HomoloGene: 50962 GeneCards: GPR62
Gene location (Human)
Chr.	Chromosome 3 (human)
End	51,957,499 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	106,343,137 bp
RNA expression pattern
	Top expressed in
	inferior ganglion of vagus nerve; ; internal globus pallidus; ; subthalamic nucleus; ; endothelial cell; ; ventral tegmental area; ; corpus callosum; ; substantia nigra; ; external globus pallidus; ; medulla oblongata; ; putamen;
	Top expressed in
	seminiferous tubule; ; substantia nigra; ; anterior horn of spinal cord; ; suprachiasmatic nucleus; ; pontine nuclei; ; lateral geniculate nucleus; ; spermatocyte; ; ventral tegmental area; ; spermatid; ; dorsal tegmental nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; protein binding; identical protein binding; arrestin family protein binding;
Cellular component	integral component of membrane; receptor complex; membrane; plasma membrane; endosome; endosome membrane;
Biological process	signal transduction; G protein-coupled receptor signaling pathway; positive regulation of cAMP-mediated signaling; inositol phosphate-mediated signaling;
	Sources:Amigo / QuickGO
Orthologs
	118442
	436090
	ENSG00000180929
	ENSMUSG00000091735
	Q9BZJ7
	Q80UC6
	NM_080865
	NM_001159652
	NP_543141
	NP_001153124
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 62 is a protein that in humans is encoded by the GPR62 gene.^[5]^[6]

G protein–coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000180929 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000091735 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Lee DK, George SR, Cheng R, Nguyen T, Liu Y, Brown M, Lynch KR, O'Dowd BF (Feb 2001). "Identification of four novel human G protein-coupled receptors expressed in the brain". Brain Res Mol Brain Res. 86 (1–2): 13–22. doi:10.1016/S0169-328X(00)00242-4. PMID 11165367.
1 2 "Entrez Gene: GPR62 G protein-coupled receptor 62".

Takeda S, Kadowaki S, Haga T, et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878. S2CID 7116392.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000180929 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000091735 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11165367-5] Lee DK, George SR, Cheng R, Nguyen T, Liu Y, Brown M, Lynch KR, O'Dowd BF (Feb 2001). "Identification of four novel human G protein-coupled receptors expressed in the brain". Brain Res Mol Brain Res. 86 (1–2): 13–22. doi:10.1016/S0169-328X(00)00242-4. PMID 11165367.

[entrez-6] 1 2 "Entrez Gene: GPR62 G protein-coupled receptor 62".

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References

Further reading