Ro20-8065

Ro20-8065
Legal status
Legal status
Identifiers
IUPAC name
  • 7,8-dichloro-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one
CAS Number
PubChem CID
ChemSpider
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H9Cl2FN2O
Molar mass323.15 g·mol−1
3D model (JSmol)
SMILES
  • C1C(=O)NC2=CC(=C(C=C2C(=N1)C3=CC=CC=C3F)Cl)Cl
InChI
  • InChI=1S/C15H9Cl2FN2O/c16-10-5-9-13(6-11(10)17)20-14(21)7-19-15(9)8-3-1-2-4-12(8)18/h1-6H,7H2,(H,20,21)
  • Key:XINLNKMOSCQFJB-UHFFFAOYSA-N

Ro20-8065 (8-Chloronorflurazepam) is a benzodiazepine derivative with anticonvulsant and muscle relaxant effects,[1] which has been sold as a designer drug.[2]

See also

References

  1. ↑ Zhang W, Koehler KF, Harris B, Skolnick P, Cook JM (March 1994). "Synthesis of benzo-fused benzodiazepines employed as probes of the agonist pharmacophore of benzodiazepine receptors". Journal of Medicinal Chemistry. 37 (6): 745–57. doi:10.1021/jm00032a007. PMID 8145224.
  2. ↑ Catalani V, Botha M, Corkery JM, Guirguis A, Vento A, Scherbaum N, Schifano F (July 2021). "The Psychonauts' Benzodiazepines; Quantitative Structure-Activity Relationship (QSAR) Analysis and Docking Prediction of Their Biological Activity". Pharmaceuticals (Basel, Switzerland). 14 (8): 720. doi:10.3390/ph14080720. PMC 8398354. PMID 34451817.


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