O-1125

O-1125
Identifiers
	IUPAC name 6-[(6aR,10aR)-1-Hydroxy-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-3-yl]-N,N,6-trimethylheptanamide;
PubChem CID	9909689;
ChemSpider	8085340;
Chemical and physical data
Formula	C26H39NO3
Molar mass	413.602 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=CC[C@@H]2[C@@H](C1)C3=C(C=C(C=C3OC2(C)C)C(C)(C)CCCCC(=O)N(C)C)O;
	InChI InChI=1S/C26H39NO3/c1-17-11-12-20-19(14-17)24-21(28)15-18(16-22(24)30-26(20,4)5)25(2,3)13-9-8-10-23(29)27(6)7/h11,15-16,19-20,28H,8-10,12-14H2,1-7H3/t19-,20-/m1/s1; Key:QGBHDXFADXCURB-WOJBJXKFSA-N;
	(verify)

O-1125 (3-(1,1-dimethylhexyl-6-dimethylcarboxamide)-Δ8-tetrahydrocannabinol) is a research chemical which is a cannabinoid derivative. It has analgesic effects and is used in scientific research. It is a potent CB₁ full agonist with a K_i of 1.16 nM.^[1]

References

↑ Griffin G, Wray EJ, Martin BR, Abood ME (1999). "Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum". British Journal of Pharmacology. 128 (3): 684–688. doi:10.1038/sj.bjp.0702806. PMC 1571656. PMID 10516649.

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[1] Griffin G, Wray EJ, Martin BR, Abood ME (1999). "Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum". British Journal of Pharmacology. 128 (3): 684–688. doi:10.1038/sj.bjp.0702806. PMC 1571656. PMID 10516649.

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